Rapidly assess color development of prototype self-tanning formulations, competitive formulas and novel raw materials.
For many researchers, the most challenging part of testing the performance of sunless self-tanning products, is recruiting a reliable group of human test subjects that are willing to have numerous test formulations applied to their forearms. And then getting these test subjects to return for all their readings through the course of a multi-day study.
The IMS In Vitro Sunless Kit replaces the variability of human volunteers with VITRO-SKIN® – an advanced testing substrate engineered to mimic the color development of human skin when exposed to formulations containing DHA or other sunless tanning actives.
Initial results available in eight hours, and a full comparison of eight products can be completed in just 24 hours! Think how much this will accelerate your formulation development process — and the speed of you filing new self-tanner formulation patents.
Your product testing studies will no longer be delayed, or lose statistical significance, because your human test subject(s) missed their measurement times (due to urgent meetings, unplanned work travel, sick days, etc.).
VITRO-SKIN® eliminates the variability, problems and potential hazards of working with excised human skin or animal skin, allowing you to rapidly-generate, predictive-data on prototype formulations and competitive products.
- Surface topography effectively mimics human skin, so products spread naturally during application.
- Similar pH, critical surface tension, and ionic strength as human skin, so emulsions break the same as on human skin.
- Optimized components, with excellent consistency lot-to-lot, insure reproducible effects.
- More reproducible results compared to human skin.
- Low lot-to-lot variability means more comparable results study-to-study.
- Individually heat-sealed single sheet packaging means immediate availability of fresh material with less waste.
- Always available for testing. No more scheduling your testing around your human test subjects’ availabilities.
Introducing The IMS In Vitro Sunless Testing Kit
We have bundled everything you need to start screening raw materials, product prototypes and competitive formulas in a convenient, easy to use sunless testing kit. The IMS In Vitro Sunless Kit gets you up and running quickly. Using the proven SmartProbe 400 color probe with SmartConnect software to drop your L*a*b* color readings directly into your MS Excel spreadsheet (while avoiding the transcription errors and the wasted hours of manual data entry). The IMS In Vitro Sunless Test Kit, contains everything you need to get up and running fast. It includes:
Substrate and Equipment
- Three sheets of VITRO-SKIN®
- Two IMS Hydration Chambers
- Four Treatment Racks
- One Foam Block (for product application)
- Eight 6 x 6 cm sample holders
- Twelve finger cots
SmartProbe 400 Colorimeter
- IMS SmartProbe 400 Colorimeter (with non-volatile calibration memory and integrated RS-232 communication)
- SmartProbe 400 Calibration Tile
- RS-232 Interface SmartCable
- AC Adapter
SmartConnect Software
- IMS SmartConnect Software (for direct data entry of L*a*b* data into MS Excel)
International Journal of Cosmetic Science, 2002, 24, 1-8
Development of an in vitro efficiency test for self-tanning formulations
R. Jerrmann, M. Toumiat and D. Imfeld
Pentapharm Ltd, Engelgasse 109, CH-4002 Basel, Switzerland
Received 20 April 2001. Accepted 26 July 2001.
Keywords: erythrulose, dihydrosyacetone, in vitro efficacy test, self-tanning formulations, skin colour assessment, vitro skin
Synopsis
In the last few years, the desire to acquire a tan without sunbathing has grown. In response, many cosmetic companies have produced self-tanning preparations. However, to optimize these formulations, a suitable model to assess the colour induced on the skin remains to be developed. We have developed an in vitro method using a synthetic skin in order to study the efficacy of self-tanning formulations. The in vitro test was then used to study the influence of cosmetic ingredients upon the colour induced by erythrulose- or dihydroxyacetone-containing formulations. Finally, an in vivo study allowed us to relate the results obtained in vitro with those found on human skin. The results show that this in vitro test system is a reliable tool to predict the efficacy of self-tanning products.
PROCEEDINGS OF THE 20TH IFSCC CONGRESS
USE OF SYNTHETIC SKIN FOR IN-VITRO EVALUATION OF PHOTPROTECTIVE EFFICACY OF SUNSCREENS: APPLICATION TO DIFFERENT TYPE OF EMULSIONS
N.S. Tokgoz, G. Marginean-Lazar, A. Ponte, A.E. Fructus
Laboratoires Dermatologiques Lutsia, Boots Healthcare International, Paris, France 2Hermal, Boots Healthcare International, Hamburg, Germany 3Ecole Biolgie Industrielle, Paris, France
Several methods exist that evaluate sunscreens efficacy for ultraviolet radiations (FDA, DIN, COLIPA, Australian standards etc.) and it is generally accepted that the determination of sun protection faction (SPF) on humans is the most reliable one.
PROCEEDINGS OF THE 20TH IFSCC CONGRESS
SUNSCREEN O1/W/O2, MULTIPLE EMULSION WITH ORGANIC AND MINERAL UV ABSORBERS.
L. Ferrero, K. Golz, S. Bouttes, L. Zastrow
INTRODUCTION:
Numerous studies have revealed the interest of multiple emulsions for the cosmetic industry (1)-(4). These complex systems present several advantages compared to other systems: high entrapment capacity, possible protection of fragile substances encapsulated into the internal
PROCEEDINGS OF THE 20TH IFSCC CONGRESS
SPECTROSCOPY OF SUNSCREEN PRODUCTS: HOW TO EXPLAIN THE SPECIAL SHAPE OF UV CURVES OBTAINED FROM IN VITRO SPF TESTS.
Authors: L. Ferrero, A.M. Orcet, L. Zastrow
INTRODUCTION:
Numerous attempts have been made to understand how sunscreen preparations protect against UV radiations (1)-(4). Normally, the final UV absorption of a sunscreen product should depend on absorption curves of each UV filters placed within the preparation. However, it is now trivial to remark the bad accordance between SPF(s) directly calculated from spectroscopic absorbances of pure UV filters (obtained from dilute solutions and measured in 1 cm quartz
PROCEEDINGS OF THE 20TH IFSCC CONGRESS
RHEOLOGICAL PROPERTIES AND FUNCTIONALITY OF SUNSCREEN FORMULATIONS
A. Semenzato, M. Poropat, M. Marcazzan, A. Bettero
Centro di Cosmetologia Chimica, Dipartimento di Scienze Farmaceutiche, Universita di Padova Via Marzolo 5, 35131 Padova, Italy
INTRODUCTION:
The use of polymeric additives as raw materials 1, 2, 3, 4, which could increase the SPF value of sunscreens, has grown up much lately.
PROCEEDINGS OF THE 20TH IFSCC CONGRESS
COMPARISON OF UVA/UVB PROTECTION OF FOUNDATION FORMULATIONS BETWEEN SPHERICAL POLYMER MATRIX COMPOSITES VERSUS NANOFINE METAL OXIDES ARE EVALUATED IN TWO SPF IN VITRO METHODS.
Jaana Printz and Alain Saintrond*
Cosmetic Innovations and Technologies, 13 Rue des Livraindrieres, Dreux, France.
*Creations Couleurs, Research Laboratory, 6 rue Jules Pasdeloup, 28100 Dreux, France.
Key Words: Colour stability, Photostability, Spherical Polymer Matrix Composites, In vitro SPF
Patent# | Description | Company |
6,740,313 | Compositions For Giving The Skin A Coloration Similar To That Of A Natural Tan, Based On A Pigment Of The Monascus Type, And Uses Thereof | L’Oreal S.A. |
9,751,063 | Emulsion Compositions And Applications Therefor | Momentive Performance Materials Inc. |
6,406,682 | Saxifraga Extracts For Artificially Tanning Human Skin | Societe L’Oreal |
8,815,219 | Sunless Tanning With Pyranones And Furanones | Conopco, Inc. |
8,398,959 | Compositions And Methods For Imparting A Sunless Tan With Functionalized Adjuvants | Conopco, Inc. |
8,241,614 | Compositions And Methods For Imparting A Sunless Tan | Conopco, Inc. |